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- Article] CASINO: Surgical or Nonsurgical Treatment for cervical radiculopathy, a randomised controlled trial
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DocNo of ILP: 45
Doc. Type: Article
Title: CASINO: Surgical or Nonsurgical Treatment for cervical radiculopathy, a randomised controlled trial
Authors: van Geest, S; Kuijper, B; Oterdoom, M; van den Hout, W; Brand, R; Stijnen, T; Assendelft, P; Koes, B; Jacobs, W; Peul, W; Vleggeert-Lankamp, C
Full Name of Authors: van Geest, Sarita; Kuijper, Barbara; Oterdoom, Marinus; van den Hout, Wilbert; Brand, Ronald; Stijnen, Theo; Assendelft, Pim; Koes, Bart; Jacobs, Wilco; Peul, Wilco; Vleggeert-Lankamp, Carmen
Keywords by Author: Cervical herniated disc; Cervical radicular syndrome; Anterior discectomy; Foraminotomy; Cost-effectiveness; Conservative treatment; Randomized controlled trial; Shared decision making
Keywords Plus: VISUAL ANALOG SCALE; NONOPERATIVE MANAGEMENT; DISC HERNIATION; SURGERY; PAIN; FUSION; PHYSIOTHERAPY; MULTICENTER; RELIABILITY; DISKECTOMY
Abstract: Background: Cervical radicular syndrome (CRS) due to a herniated disc can be safely treated by surgical decompression of the spinal root. In the vast majority of cases this relieves pain in the arm and restores function. However, conservative treatment also has a high chance on relieving symptoms. The objective of the present study is to evaluate the (cost-) effectiveness of surgery versus prolonged conservative care during one year of follow-up, and to evaluate the timing of surgery. Predisposing factors in favour of one of the two treatments will be evaluated. Methods/design: Patients with disabling radicular arm pain, suffering for at least 2 months, and an MRI-proven herniated cervical disc will be randomised to receive either surgery or prolonged conservative care with surgery if needed. The surgical intervention will be an anterior discectomy or a posterior foraminotomy that is carried out according to usual care. Surgery will take place within 2-4 weeks after randomisation. Conservative care starts immediately after randomisation. The primary outcome measure is the VAS for pain or tingling sensations in the arm one year after randomisation. In addition, timing of surgery will be studied by correlating the primary outcome to the duration of symptoms. Secondary outcome measures encompass quality of life, costs and perceived recovery. Predefined prognostic factors will be evaluated. The total follow-up period will cover two years. A sample size of 400 patients is needed. Statistical analysis will be performed using a linear mixed model which will be based on the 'intention to treat' principle. In addition, a new CRS questionnaire for patients will be developed, the Leiden Cervical Radicular Syndrome Functioning (LCRSF) scale. Discussion: The outcome will contribute to better decision making for the treatment of cervical radicular syndrome.
Cate of OECD: Clinical medicine
Year of Publication: 2014
Business Area: other
Detail Business: medicine & science
Country: England
Study Area: development, development, adolescent, decision, syndrome
Name of Journal: BMC MUSCULOSKELETAL DISORDERS
Language: English
Country of Authors: [van Geest, Sarita; Jacobs, Wilco; Peul, Wilco; Vleggeert-Lankamp, Carmen] Leiden Univ, Med Ctr, Dept Neurosurg, NL-2300 RC Leiden, Netherlands; [Kuijper, Barbara] Maasstad Hosp Rotterdam, Dept Neurol, Rotterdam, Netherlands; [Oterdoom, Marinus] Martini Hosp, Dept Neurosurg, Groningen, Netherlands; [van den Hout, Wilbert] LUMC, Dept Med Decis Making, NL-2300 RC Leiden, Netherlands; [Brand, Ronald] LUMC, Dept Med Stat, NL-2300 RC Leiden, Netherlands; [Stijnen, Theo] Radboud Univ Hosp Nijmegen, Dept Primary & Community Care, Nijmegen, Netherlands; [Assendelft, Pim] Univ Med Ctr Rotterdam, Dept Gen Practice, Rotterdam, Netherlands
Press Adress: Vleggeert-Lankamp, C (reprint author), Leiden Univ, Med Ctr, Dept Neurosurg, POB 9600, NL-2300 RC Leiden, Netherlands.
Email Address: Cvleggeert@lumc.nl
Citaion:
Funding: ZonMw, the Dutch Organisation for Health Research and Development
Lists of Citation: Abd-Alrahman N, 1999, ACTA NEUROCHIR, V141, P1089, DOI 10.1007/s007010050487; Anderson Paul A, 2004, Spine J, V4, p303S, DOI 10.1016/j.spinee.2004.07.026; Broadbent E, 2006, J PSYCHOSOM RES, V60, P631, DOI 10.1016/j.jpsychores.2005.10.020; Bush K, 1997, SPINE, V22, P183, DOI 10.1097/00007632-199701150-00009; Carette S, 2005, NEW ENGL J MED, V353, P392, DOI 10.1056/NEJMcp043887; Caridi John M, 2011, HSS J, V7, P265; CARLSSON AM, 1983, PAIN, V16, P87, DOI 10.1016/0304-3959(83)90088-X; Denollet J, 2012, BMC PUBLIC HEALTH, V12, P46; Engquist M, 2013, SPINE, V38, P1715, DOI 10.1097/BRS.0b013e31829ff095; Fordyce WE, 1976, BEHAV METHODS CHRONI; Fouyas IP, 2002, SPINE, V27, P736, DOI 10.1097/00007632-200204010-00011; Hacker RJ, 2000, SPINE, V25, P2646, DOI 10.1097/00007632-200010150-00017; Heckmann JG, 1999, J SPINAL DISORD, V12, P396; HUSKISSO.EC, 1974, LANCET, V2, P1127; Kuijper B, 2009, EUR J NEUROL, V16, P15, DOI 10.1111/j.1468-1331.2008.02365.x; Kuijper B, 2009, BMJ-BRIT MED J, V339, P952; MAIN CJ, 1992, SPINE, V17, P42, DOI 10.1097/00007632-199201000-00007; Mochida K, 1998, SPINE, V23, P990, DOI 10.1097/00007632-199805010-00005; Moreland Douglas B, 2004, Spine J, V4, P184, DOI 10.1016/j.spinee.2003.05.001; Oostenbrink JB, 2004, EUR RESPIR J, V23, P241, DOI 10.1183/09031936.03.00083703; Persson LCG, 1997, SPINE, V22, P751, DOI 10.1097/00007632-199704010-00007; RADHAKRISHNAN K, 1994, BRAIN, V117, P325, DOI 10.1093/brain/117.2.325; Ramadan AS, 2007, EUR J ORTHOP SURG TR, V17, P513, DOI 10.1007/s00590-007-0242-0; Saal JS, 1996, SPINE, V21, P1877, DOI 10.1097/00007632-199608150-00008; Salemi G, 1996, ACTA NEUROL SCAND, V93, P184; Sampath P, 1999, SPINE, V24, P591, DOI 10.1097/00007632-199903150-00021; Schellingerhout JM, 2012, QUAL LIFE RES, V21, P659, DOI 10.1007/s11136-011-9965-9; Schiffer AA, 2005, EUR J CARDIOV PREV R, V12, P341, DOI 10.1097/01.hjr.0000173107.76109.6c; Stiggelbout AM, 1996, INT J TECHNOL ASSESS, V12, P291; Tewarie RDSN, 2007, EUR SPINE J, V16, P1411, DOI 10.1007/s00586-007-0309-y; van den Hout WB, 2008, BRIT MED J, V336, P1351, DOI 10.1136/bmj.39583.709074.BE; VERNON H, 1991, J MANIP PHYSIOL THER, V14, P409; Vinas FC, 2001, J CLIN NEUROSCI, V8, P542, DOI 10.1054/jocn.2000.0894; Wainner RS, 2000, J ORTHOP SPORT PHYS, V30, P728; YOSS RE, 1957, NEUROLOGY, V7, P673
Number of Citaion: 35
Publication: BIOMED CENTRAL LTD
City of Publication: LONDON
Address of Publication: 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND
ISSN: 1471-2474
29-Character Source Abbreviation: BMC MUSCULOSKEL DIS
ISO Source Abbreviation: BMC Musculoskelet. Disord.
Volume: 15
Version:
Start of File:
End of File:
DOI: 10.1186/1471-2474-15-129
Number of Pages: 7
Web of Science Category: Orthopedics; Rheumatology
Subject Category: Orthopedics; Rheumatology
Document Delivery Number: AG8RN
Unique Article Identifier: WOS:000335686000001
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