경마 | Cases & Studies in Horse Racing | 赛马
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- Article] Effects of racing on lymphocyte proliferation in horses
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DocNo of ILP: 6269
Doc. Type: Article
Title: Effects of racing on lymphocyte proliferation in horses
Authors: Nesse, LL; Johansen, GI; Blom, AK
Full Name of Authors: Nesse, LL; Johansen, GI; Blom, AK
Keywords by Author:
Keywords Plus: IMMUNE FUNCTION; EXERCISE STRESS; PLASMA
Abstract: Objective-To measure the lymphocyte proliferation response in horses 12 to 16 hours after completion of a race. Animals-8 Thoroughbreds that competed in 14 races and 3 control Thoroughbreds that did not race. Procedure-Horses participated in races during the late afternoon or evening. Venous blood samples were collected on a morning before a race (1 or 2 days before the race or on the day of the race), on the afternoon of a race (40 to 60 minutes after the race), and on the morning of the day after a race (12 to 16 hours after the race). Lymphocyte proliferation responses and WBC count were measured in samples obtained in the mornings. Plasma cortisol was measured in all samples. Results-Lymphocyte proliferation responses were significantly reduced and WBC counts significantly increased 12 to 16 hours after a race. Plasma cortisol concentrations were significantly increased 40 to 60 minutes after a race. In samples from the control horses, lymphocyte proliferation responses, WBC counts, or plasma cortisol concentrations did not differ significantly among time periods. Conclusions and Clinical Relevance A decrease in proliferative responses of circulating lymphocytes can be found as late as 12 to 16 hours after a horse participates in a race. Although the clinical consequences of these exercise-related alterations of the immune response are not yet known, managers of horses should take into account that the immune system of a horse may be affected by racing.
Cate of OECD: Veterinary science
Year of Publication: 2002
Business Area: other
Detail Business: medicine & science
Country: USA
Study Area:
Name of Journal: AMERICAN JOURNAL OF VETERINARY RESEARCH
Language: English
Country of Authors: Natl Vet Inst, Dept Bacteriol, N-0033 Oslo, Norway; Norwegian Sch Vet Sci, Inst Biochem Physiol & Nutr, N-0033 Oslo, Norway
Press Adress: Nesse, LL (reprint author), Natl Vet Inst, Dept Bacteriol, POB 8156 DEP, N-0033 Oslo, Norway.
Email Address:
Citaion:
Funding:
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Number of Citaion: 23
Publication: AMER VETERINARY MEDICAL ASSOC
City of Publication: SCHAUMBURG
Address of Publication: 1931 N MEACHAM RD SUITE 100, SCHAUMBURG, IL 60173-4360 USA
ISSN: 0002-9645
29-Character Source Abbreviation: AM J VET RES
ISO Source Abbreviation: Am. J. Vet. Res.
Volume: 63
Version: 4
Start of File: 528
End of File: 530
DOI: 10.2460/ajvr.2002.63.528
Number of Pages: 3
Web of Science Category: Veterinary Sciences
Subject Category: Veterinary Sciences
Document Delivery Number: 535ZC
Unique Article Identifier: WOS:000174675400010
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